Introduction: Periodontal disease has become a global health concern, affecting 20-50% of the population and negatively affecting the patient’s quality of life by compromising function and aesthetics through rapid tooth loss. The implant prosthetic all on six concept offers a promising solution for rehabilitating these patients with fixed restorations immediately after tooth extractions. Case Presentation: Our manuscript presents two maxillary full-arch rehabilitation cases using the all on six concept. Both patients (female and male, 45 and 49 years) with chronic periodontal disease background were treated similarly: clinical and radiological examination; diagnosis; Cone bean-computed tomography examination for accurate treatment planning; extractions of all the maxillary teeth with pathological mobility; immediate implant placement (six implants) with a torque at least 35 N/cm; attachment of straight and angulated multiunit abutments torqued with 25 N/cm; PMMA provisional restorations (facilitated by enhanced primary stability); control radiographs after the osseointegration period (six months), and the realization of the screw-retained final restorations (zirconia-ceramics in case of the female patient and metal ceramics for the male patient); occlusal adjustments; periodic follow-up. Conclusions: Post-extraction implant placement and temporary restorations inserted in both full-arch rehabilitation cases improved masticatory function and enhanced physical appearance, increasing the quality of life. Achieving well-adapted and integrated prosthetic works requires thorough analysis and design. The all on six systems are a reliable alternative for complete dentures.

DOI: https://doi.org/10.62838/ASMJ.2025.1.05